Virucidal Suspension Tests
Test Purpose
The purpose of this test is to
evaluate the antiviral
properties of a product against
a specific virus when exposed
(in suspension) for a specified
exposure time(s). This protocol
follows the Standard Test Method
for Efficacy of Antimicrobial
Agents Against Viruses in
Suspension (ASTM E 1052).
Test Summary
A suspension of virus is exposed
to the use dilution of the
product. At each pre-determined
exposure time an aliquot is
removed, neutralized by serial
dilution, and assayed for the
presence of virus. The positive
virus controls, cytotoxicity
controls, and neutralization
controls are assayed in
parallel. Antiviral properties
of the product will be evaluated
and compared at the specified
concentrations and time
intervals.
Topical Antimicrobial tests include:
l Microbial Time-Kill Tests
l Minimum
Inhibitory Concentration (MIC)
Tests and
l Minimum
Bactericidal Concentration (MBC)
Tests
l AOAC Available Chlorine Equivalency Tests
l Virucidal Suspension Tests
l Virucidal Efficacy on Surrogate Skin Surfaces (Ex-Vivo)
l Zone of Inhibition Tests
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